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GIM3 (FATA), A phase III study comparing anastrozole, letrozole and exemestane, upfront (for 5 years) or sequentially (for 3 years after 2 years of tamoxifen). Comparison of anterior pituitary hormone levels between the inferior petrosal. A phase III study comparing anastrozole, letrozole and exemastane, upfront. Phase III study comparing exemestane with tamoxifen as first-line. cancer. comparison of the aromatase inhibitors letrozole and anastrozole. E1*Comparison of toxicity after 2 years of adjuvant anastrozole (A) or exemestane (E) or letrozole (L) or tamoxifen (T). 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