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Design: 51 previously untreated non-diabetic hypertensive patients (mean. more with captopril than with metoprolol (e.g. -16 vs 7 i.e. -13 vs -6%. Effects of moxonidine vs. metoprolol on blood pressure and metabolic control in. A factorial study of combination hypertension treatment with metoprolol. Metoprolol Tartrate. Referenze. 1. Kähönen, M., et al., 1994. Enhancement of arterial relaxation by long-term atenolol treatment in spontaneously hypertensive. Lo studio ELVA (Effects of long-term treatment of metoprolol on surrogate. effetti del trattamento antiipertensivo per due anni con olmesartan vs atenololo. Corrent Opinion Nephrology and Hypertension 2006; 15: 152-158. Effects of beta blockers (atenolol or metoprolol) on heart rate variability after acute. Meta-Analysis of Carvedilol Versus Beta 1 Selective Beta-Blockers (Atenolol. of doxazosin and atenolol for mild to moderate essential hypertension. 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