1 is a X-ray diffraction pattern of a solid dispersion of atorvastatin calcium and Eudragit™ E PO prepared in Example 2b. Fig. 2 is a differential. new/1291-1-11478.php Water Solubility Enhancement of Atorvastatin by Solid Dispersion Method. Riaz Uddin, Farzana Ali, Subrata Kumar Biswas. new/3293-1-10361.php The purpose of the current study is to prepare Atorvastatin calcium solid dispersions by using various techniques and to characterize the solid-state properties of. The aim of the present study was to improve the solubility and dissolution rate of atorvastatin (ATV), a slight water-soluble drug, by solid dispersion (SD). Physicochemical characterization and dissolution study of solid dispersions of. 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