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UA may be a risk factor for cardiovascular diseases and a negative prognostic marker for. aorto-coronarico, il trattamento con allopurinolo ha ridotto il danno. Improvement of cardiac function by allopurinol in patients undergoing cardiac surgery. On-pump versus off-pump coronary artery bypass surgery in high-risk. Department of Cardiovascular Sciences, University of Cagliari, Cagliari, Italy. in FMD after 3 months of therapy with allopurinol in hyperuricemic patients. (FMD) compared with matched controls with normal UA levels and elevated CV risk. Effect of allopurinol in chronic kidney disease progression and cardiovascular risk. Clinical journal of the American Society of Nephrology : CJASN 2010 Aug. 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