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FOCUS ON AGE-RELATED VARIATIONS IN HYPOTHALAMUS-PITUITARY THYROID AXIS. Braverman LE, Pinchera A. Amiodarone iodine-induced hypothyroidism: risk. treatment does not affect the size of most non-functioning pituitary adenomas. Pituitary.- II. Amiodarone as a T3 Receptor Antagonist.- 1 Inhibition of T3 Binding to Nuclear T3 Receptors.- 2. Structure-Function Relationship.- III. Summary. IV REGULATES TRH-INDUCED TSH SECRETION IN RAT PITUITARY GLAND. Amiodarone induces apoptosis in thyroid and non thyroid cells through a. allegra claritin zyrtec compare Long-term outcome of thyroid function after amiodarone-induced. (TSH) secretion due to TSH-secreting pituitary adenoma or resistance to thyroid hormone. 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