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P-gp. +12–60%. voriconazole; posaconazole. bleeding risk. Pharmacodynamic interactions – antiplatelet drugs, NSAIDs. or yeast infections, like fluconazole, itraconazole, ketoconazole, and voriconazole;. Also known to interact with. Increases in amiodarone and desethylamiodarone concentrations were observed after an increase in the amiodarone dosage. amiodarone, chinidina), cisapride, dofetilide, H1 antagonisti [.]. 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